Michael Koulianos emphasizes the significance of the ascension of Jesus as a pivotal event that directly correlates with the coming of the Holy Spirit. He highlights that Jesus' ascension is not just a physical elevation but a profound declaration of His authority and the fulfillment of God's plan for humanity. Koulianos encourages believers to understand the connection between Jesus' glorification and the empowerment of the Holy Spirit, which marks the beginning of a new age in the church. He stresses the importance of scripture in building spiritual stature and the necessity of unity among believers to experience the fullness of the Spirit. Ultimately, the sermon calls for a deeper recognition of Jesus' lordship and the transformative power of the Holy Spirit in the life of the church.