Mike Bickle challenges the congregation to step out of their comfort zones and embrace a deeper relationship with God, as illustrated in the Song of Solomon. He emphasizes that knowing about God is not enough; true engagement requires a response to His call for deeper partnership and obedience. Bickle highlights the importance of recognizing God's love and power, encouraging believers to trust Him even when faced with fear and uncertainty. He reassures that God views our hesitations as immaturity rather than rebellion, inviting us to grow in our faith and obedience. Ultimately, the sermon calls for a commitment to rise up and follow God's lead into new challenges and opportunities for spiritual growth.