A.W. Tozer emphasizes the importance of the exclamatory expression 'Oh!' in our relationship with God, contrasting it with the intellectual confines of theology. He argues that true spiritual experience transcends mere knowledge and invites a heartfelt response to God's presence, which often leaves us in silence and awe. Tozer warns that losing the 'Oh!' in our prayers signifies a dangerous shift towards self-reliance and a lack of genuine connection with God. He encourages Christians to maintain a sense of wonder and reverence in their spiritual lives, ensuring that their prayers are heartfelt rather than merely routine. The sermon concludes with a plea to never lose that profound sense of awe before God.