George Mueller emphasizes the necessity of prioritizing soul nourishment through the Word of God each morning before engaging in prayer or service. He shares his personal transformation from a prayer-first approach to one that begins with meditation on Scripture, which leads to a more fruitful and spiritually fulfilling prayer life. By focusing on the inner man's nourishment, Mueller finds that his heart is prepared for communion with God, resulting in a peaceful and happy state. He encourages believers to seek spiritual food daily, as it is essential for enduring life's trials and serving others effectively. This practice has brought him immense spiritual profit and strength over the years.