Zac Poonen emphasizes the necessity of being emptied of self to truly embrace the Christ-life, drawing parallels between the lives of Paul and Abraham. He illustrates that true faith and worship require a relinquishing of self-sufficiency, as seen in Abraham's journey of trusting God for a son and his willingness to sacrifice Isaac. Poonen highlights that God's blessings are not just for personal gain but are meant to flow through us to others, and that our service must stem from dependence on the Holy Spirit rather than human effort. The sermon calls believers to recognize their impotence without God and to offer everything, including their most cherished gifts, back to Him in worship. Ultimately, Poonen challenges the congregation to embrace the cross as the pathway to spiritual power and fulfillment in their lives.