Mike Bickle discusses the significance of the fifth and sixth seals in Revelation 6:9-17, emphasizing the power of prayer and the role of martyrs in the end times. He explains that the prayers of the martyrs in heaven, crying out for justice, fuel a prayer movement on earth that will intensify as the return of Christ approaches. The sixth seal introduces supernatural judgments that reflect God's response to these prayers, highlighting the urgency and importance of intercession in the current age. Bickle encourages believers to become familiar with these passages to lift the fog of misunderstanding and to recognize the dynamic nature of prayer in God's plan. Ultimately, he asserts that the prayer movement will be a critical force against the antichrist's kingdom.