C.H. Spurgeon emphasizes the necessity of both mouth confession and heart belief in Jesus Christ for salvation, as stated in Romans 10:9. He challenges listeners to reflect on their own faith, asking if they have openly confessed Jesus as their Savior and genuinely believe in His resurrection. Spurgeon assures that if one can affirm both, they are saved, highlighting the certainty of God's promise: 'Thou shalt be saved.' He expresses the importance of being saved from sin's guilt, power, punishment, and ultimately its very presence, celebrating the assurance of salvation through faith.