John Nelson Darby emphasizes the divine goodness of the Lord as He provides for the hungry and demonstrates His power, contrasting the disciples' limited understanding with the people's unbelief. He highlights the importance of spiritual perception, as the disciples, despite witnessing miracles, fail to grasp the true nature of Jesus' mission and the necessity of the cross. The sermon illustrates the need for self-denial and the acceptance of suffering as part of following Christ, warning against the distractions of worldly desires. Darby concludes with a call to recognize the eternal value of the soul and the importance of standing firm in faith amidst a corrupt world, reminding believers of the glory that awaits those who are not ashamed of Christ.