Mike Bickle emphasizes the significance of Cyrus in Isaiah 45, portraying him as a prophetic figure who represents modern-day individuals called to influence society for God's glory. He highlights that Cyrus, a pagan king, was chosen by God to fulfill divine purposes, including the rebuilding of Jerusalem and the temple, despite not yet being born. Bickle encourages listeners to embrace their own 'Cyrus calling' by seeking divine wisdom, forming alliances, and understanding their roles in the larger narrative of God's plan. He stresses the importance of prayer and prophetic insight in fulfilling these assignments, urging the audience to connect with intercessors and prophetic voices. Ultimately, the message is about recognizing God's sovereignty and the hidden riches He provides for those who are obedient to His calling.