J.R. Miller addresses the causes of failure in life, emphasizing that many lives resemble wrecked ships, lost to the depths of despair due to poor choices and lack of direction. He highlights various factors contributing to failure, including bad company, lack of purpose, and moral cowardice, while stressing the importance of hard work, self-discipline, and integrity. Miller warns against the allure of ease and pleasure, which can lead to missed opportunities for growth and success. He encourages young men to build character and seize the chances life offers, reminding them that a noble life is too valuable to waste. Ultimately, he calls for reliance on Christ to ensure that one does not fail in their endeavors.