George Mueller emphasizes the foundational principles of the Scriptural Knowledge Institution, asserting that every believer is called to support the cause of Christ without seeking worldly patronage or compromising on scriptural integrity. He outlines the institution's commitment to operate solely under God's guidance, avoiding debt and relying on prayer for provision. The institution aims to establish schools based on scriptural principles, circulate the Holy Scriptures, and support missionary efforts, ensuring that all involved in teaching and leadership are believers. Mueller stresses that success is measured by God's blessing rather than financial contributions or numbers. Ultimately, the institution seeks to fulfill its mission in a manner that honors God and aligns with biblical teachings.