Mike Bickle emphasizes the significance of understanding the Armageddon campaign to interpret current signs among Gentile nations. He explains that the final battle is not merely a conflict between nations but a direct war against God, culminating in Jesus' return to Jerusalem as the Messianic King. Bickle outlines the political and military developments leading to this event, highlighting the gathering of nations in a geographic location called Armageddon, where they will face divine judgment. He stresses that the second coming of Christ is intertwined with a military conflict, ultimately leading to the establishment of His authority over the earth. The sermon serves as a call to recognize the gravity of these prophetic events and their implications for humanity.