F.B. Meyer emphasizes the danger of being overly busy with trivial matters, drawing from the parable of a man who lost sight of his primary responsibility while preoccupied with distractions. He warns that many people fill their lives with superficial activities, neglecting the deeper purpose of influencing others and seeking salvation. Meyer highlights the fleeting nature of life and the importance of focusing on eternal values rather than ephemeral interests. He calls for a reevaluation of priorities to ensure that we do not miss the opportunity to know God and impact the lives of those around us.

Mary Wilder Tileston emphasizes the importance of seizing opportunities to do good and show kindness, as once neglected, no self-sacrifice can atone for the consequences of our negligence. She encourages believers to consider the weak, support the faint-hearted, and be patient with everyone, trusting in Jehovah's deliverance in times of trouble. Tileston also highlights the significance of living a life that lessens human sorrow and increases happiness by showing sympathy, kindness, and forgiveness towards others.

J. Wilbur Chapman preaches about the importance of seizing opportunities that God places within our grasp, emphasizing the consequences of neglecting these moments of decision. He illustrates this with the story of a guard who let a prisoner escape due to negligence, highlighting how saint and sinner alike have allowed crucial opportunities to slip away. Chapman urges Christians, Christian workers, parents, and the unsaved to be vigilant and not let these moments pass, drawing examples from the Bible of those who embraced or missed their opportunities for salvation.