F.B. Meyer explores the relationship between Edom and Israel, symbolizing the ongoing struggle between the flesh and the spirit. He emphasizes that, like Edom's repeated attempts to regain independence, we often battle our own sinful nature. Meyer draws parallels to Jesus as the mighty Conqueror who triumphs over our spiritual foes, urging us to surrender our conflicts to Him completely. He encourages believers to stop relying on their own efforts and instead allow Jesus to handle their struggles with sin and temptation. The sermon calls for a total resignation of the fight to Christ, who has already secured victory on our behalf.