David Wilkerson emphasizes that true victory over temptation does not stem from mere religious practices like prayer or scripture memorization, but from breaking the fear of Satan's power. He explains that fear is the only weapon Satan has against us, and as long as we are afraid, we cannot resist temptation. Wilkerson reassures that Jesus has defeated the power of the devil, and once we understand this, we can face temptations without fear. The key to overcoming lies in recognizing that we are not powerless; instead, we are empowered by God to withstand any trial. Ultimately, we are called to rest in the confidence that God has already secured our victory over temptation.