Chuck Smith emphasizes Jesus' willingness to associate with sinners, highlighting the criticism He faced for dining with publicans and sinners. He explains that while there is danger in keeping bad company, Jesus came to heal the sick and call sinners to repentance, demonstrating His love and compassion. Smith points out that Jesus identifies with sinners not to partake in their sin, but to lift them out of their brokenness, fulfilling the prophecy of Isaiah. He reassures believers that Jesus is not afraid to touch the unclean to make them clean, and encourages them to approach Him boldly for mercy and grace. Ultimately, Jesus remains separate from sin, embodying holiness while reaching out to the lost.