John Nelson Darby expounds on 2 Corinthians 12, emphasizing the dual nature of Paul's experiences of visions and revelations alongside his sufferings and infirmities. He highlights that while Paul received extraordinary revelations, he remained humble, recognizing that his flesh was a hindrance, and that God's strength is made perfect in weakness. Darby explains the significance of being 'in Christ' and how it allows believers to glory in their weaknesses, as they are vessels for Christ's power. He also discusses the importance of discerning the means by which the gospel is spread, cautioning against relying on worldly methods rather than the power of the Holy Spirit. Ultimately, Darby encourages believers to trust in God's grace and to understand their identity and position in Christ.