Mike Bickle emphasizes the significance of worship in the context of God's end-time purpose as revealed in Revelation 4 and 5. He explores the beauty of God's throne and the exaltation of Jesus, highlighting how God intentionally displays His beauty to inspire worship. Bickle explains that Jesus, as a human, is destined to receive all authority and power over the earth, fulfilling God's promise to exalt Him as King. The sermon encourages believers to understand their role in this divine plan and to worship with a deeper awareness of God's glory and purpose.