Mike Bickle emphasizes the vital connection between prayer and reading the Word of God, asserting that this practice is both simple and essential for spiritual growth. He shares his personal journey of discovering how to engage with Scripture in a conversational manner, which transformed his prayer life from a mundane task into a dynamic dialogue with God. Bickle highlights the importance of not just studying the Bible for knowledge but using it as a means to interact with the living Word, Jesus. He encourages believers to express gratitude and seek deeper understanding of God's promises and exhortations as they read. Ultimately, he asserts that this practice is foundational for a vibrant spiritual life.