Andrew Murray emphasizes the significance of Jesus' ascension to the Father, which empowers believers to perform greater works through prayer in His name. He explains that the disciples, now His friends and messengers, are called to continue His work on earth, relying on the power received from the Father. Murray highlights that effective prayer is essential for effective work, and that true believers must align their requests with the mission of Christ. He encourages believers to fully commit to Jesus' work, assuring them that their prayers will be answered as they seek to glorify Him. Ultimately, Murray calls for a life of faith and prayer, urging believers to trust in the promises of Christ.