In this sermon, the speaker emphasizes that God can use anyone, regardless of their current circumstances or past mistakes. He uses the example of the man who was paralyzed for 38 years and was healed by Jesus. The speaker encourages listeners to have faith and take the first step towards obedience, just as the man on the mat did. The sermon also highlights the importance of stepping out in courage and trusting in God's provision. The speaker shares his own experience of God's faithfulness in providing for his family and emphasizes the need for discipleship and reaching out to others, particularly prisoners in Africa.