Mickey Brubaker preaches about the urgent call to missions, emphasizing the burden on our hearts to reach those who are still sitting in darkness, serving idols, and heading towards a Christ-less eternity. He highlights the responsibility Christians have to carry the vision God has given them, to see as God sees, and to be moved with compassion for those who have not heard the gospel. The sermon challenges believers to respond to God's cry for laborers in His harvest field, to preach the gospel to all nations, and to be willing to make sacrifices for the sake of Christ and His kingdom.