A.W. Tozer warns of the dire consequences of unavailing prayers during the Day of the Lord, as depicted in Revelation. He emphasizes that cries for mercy will come too late for those who have relied on human strength rather than on God. The sermon highlights the certainty of God's judgment and the futility of seeking refuge in earthly things when faced with divine wrath. Tozer calls for a recognition of the urgency to turn to Christ before it is too late, as the earth will be shaken and given to Jesus, the Worthy One.

John, in the sixth of Revelation, describes the most tragic, unavailing prayer meeting in the world's history! Cries and groans, shouts and demands, moans and whisper - all will be heard in that coming Day of the Lord when the forces of judgment are released. Even the mountains and the islands will be removed from their places. But by then, the prayers and cries of sinful men and women will be too little and too late! All of the great men of the earth, all the important people, all who have mistakenly put their trust and hope in purely human abilities will join those crying out in guilt. They will call on the crumbling rocks and mountains to fall on them to hide them from the wrath of God. I am among those who believe that the judgments of God are certain. We do not know the day nor the hour. But God is indeed going to shake the earth as it has never been shaken before, and He will turn it over to the Worthy One to whom it belongs - Jesus Christ!