Outline

The book has 5 divisions. Chapter 1 is prefatory to the whole book. While waiting for the Holy Spirit, the disciples are guided by the word of God.
In chapters 2-7, Jerusalem is the center as God lingers in grace towards the nation of Israel (compare Luke 13:6-9).
After the stoning of Stephen—chapters 8-12—the Gospel goes out first in Samaria and then to the Gentiles more generally. Cornelius is brought in, and an assembly is established amongst the Greeks in Antioch. It is there that the disciples are first called Christians. Peter is prominent.
In chapters 13-20 we have the travels and labors of the Apostle Paul. Three journeys are recorded, each beginning in Antioch and all but the last ending there. The first trip took Paul to Cyprus and from thence to Asia Minor (modern Turkey) and finally back to Antioch (13-14:26). On the second trip, the Apostle passed through Asia Minor into Europe (Acts 16) with visits in Macedonia and Achaia (15:36-18:22). The final trip begins in Antioch with the Apostle traveling through various cities of his former visits, and ends in Jerusalem (18:23-21).
From chapter 21 to the end of the book, we have Paul the prisoner carried from Jerusalem to Rome.