Adam Clarke Bible Commentary
The people shall labor in the very fire - All these superb buildings shall be burnt down. See the parallel passage, Jer 51:58 (note), and the note there.
Shall weary themselves for very vanity? - For the gratification of the wishes of ambition, and in buildings which shall be brought to naught.
Jamieson-Fausset-Brown Bible Commentary
is it not of the Lord of hosts--JEHOVAH, who has at His command all the hosts of heaven and earth, is the righteous author of Babylon's destruction. "Shall not God have His turn, when cruel rapacious men have triumphed so long, though He seem now to be still?" [CALVIN].
people . . . labour in the . . . fire . . . weary themselves for . . . vanity--The Chaldeans labor at what is to be food for the fire, namely, their city and fortresses which shall be burnt. Jer 51:58 adopts the same phraseology to express the vanity of the Chaldean's labor on Babylon, as doomed to the flames.
John Gill Bible Commentary
For the earth shall be filled with the knowledge of the glory of the Lord,.... Of the glory of the Lord Jesus Christ; of the glory of his person, as the Son of God, and truly God; which is essential to him, and underived; the same with his Father's, and what transcends the glory of all created beings; and of the glory of his office as Mediator, which itself is glorious and honourable: and this his glory lies in his fitness for it; in his faithful performance of it, and the honour given him by his Father upon it; as well as in the fulness of grace in him, which makes him appear glorious to his people; and who are continually giving glory to him as the Lord their righteousness, by exercising faith on his righteousness, and glorying in it; and as their only Saviour and Redeemer, by looking to him, and believing in him as such; and as the only Head of the church, by owning and holding to him; and as the only Mediator between God and man, by making use of him for that purpose, and not angels and saints; and as their Prophet, by hearkening to his voice, yielding a subjection to his Gospel, and submission to his ordinances; and as their Priest, by dealing with his blood and sacrifice for the atonement and pardon of their sins; and as their King, by obedience to his commands; and who will now take to himself his great power, and reign gloriously before his saints; the glory of his kingly office will be now seen and known, when this prophecy shall have its full accomplishment, and which seems greatly intended. The "knowledge" of all this glory will not be a mere notional and speculative one, but special and spiritual; an experimental knowledge, accompanied with affection, approbation, confidence, and appropriation: and "the earth will be filled with" this; that is, the inhabitants of it: this had an accomplishment in part in the times of the apostles, when they were sent into all the world to preach the Gospel to every creature, and diffused the savour of the knowledge of Christ everywhere; and had a further accomplishment in the times of Constantine, when the whole Roman empire, or all the world, became Christians; and again at the time of the Reformation, when many nations, especially in Europe, were freed from Popish darkness by the pure light of the Gospel; but will have its final accomplishment in the latter day; and which will bring on the destruction of antichrist, and seems here intended; since this is given as a reason why it will be all labour in vain to attempt the prevention of it. It will be by means of the Gospel spreading the knowledge of Christ everywhere that antichrist will fall; this is the brightness of Christ's coming, with which he will be destroyed; hence the angel, with the everlasting Gospel to preach to all nations, and with whose glory the whole earth will be lightened, is represented as preceding the fall of Babylon, and as the means of it; see Th2 2:8 and the great spread and large abundance of this knowledge communicated by the preaching of the Gospel is thus illustrated and exemplified,
as the waters cover the sea; expressing the nature of Gospel doctrines, revealing the glory of Christ and his grace, which, like waters, refresh and make fruitful; and the force and power of them, bearing down all before them, like an inundation of water when it breaks its banks; and likewise the depths of them, these being the deep things of God; and more especially the general spread and large abundance of them, and of the knowledge conveyed by them; which will fill the earth, as the waters of the sea fill up and cover the vast chasm prepared for them; see Isa 11:9.