Keith Simons explores Psalm 73, where Asaph grapples with the apparent prosperity of the wicked compared to the struggles of the righteous. Asaph confesses his envy towards the seemingly successful wicked, questioning the fairness of God's justice. However, upon entering the sanctuary of God, he gains insight into their ultimate fate and realizes that true prosperity lies in a relationship with God. The sermon emphasizes that while the wicked may appear to thrive, their end is destruction, while the faithful are guided and ultimately rewarded by God. Simons encourages believers to trust in God's goodness and to draw near to Him.