Robert Murray M'Cheyne delivers a powerful sermon on Ezekiel's vision of dry bones, illustrating the desolation of unconverted souls and the necessity of God's Spirit for true life. He emphasizes that while the bones represent the spiritually dead, the preaching of God's Word and prayer are essential for awakening them to new life. M'Cheyne highlights the importance of faith in God's promises, urging believers to prophesy to the Spirit for revival. He draws parallels between the vision and the current state of the Church, warning against mere outward appearances of godliness without the breath of the Spirit. Ultimately, he calls for a deep reliance on prayer and the Spirit's work to bring life to the spiritually dead.