Chuck Smith explores Genesis chapters 27 and 28, focusing on the complex dynamics of Isaac, Jacob, and Esau. He highlights Isaac's blindness and impending death, which leads to a deceptive scheme by Rebekah and Jacob to secure the blessing meant for Esau. Smith emphasizes God's sovereign choice in electing Jacob over Esau, illustrating that God's plans are not dependent on human actions or schemes. The sermon also reflects on Jacob's dream of the ladder reaching to heaven, symbolizing God's presence and promise to be with him. Ultimately, Smith encourages believers to recognize God's presence in their lives, even in difficult circumstances.