Zac Poonen emphasizes that man's greatest need is not material provisions like food or shelter, but rather the spiritual need for fellowship with God. He explains that while the body is important, the spirit holds greater significance, and many live with unresolved spiritual issues due to prejudice and preconceived notions. Poonen highlights that life on earth is a probationary period that determines our eternal destiny, and that true understanding of God comes through Jesus Christ, who reveals God's holiness and love. He stresses that the guilt of sin can only be removed through accepting the sacrifice of Jesus, who paid the penalty for our sins, and that individuals must actively choose to receive this pardon. Ultimately, the sermon calls for an open-minded pursuit of truth and a personal acceptance of God's grace.

Thomas Brooks addresses the question 'Who can show us any good?' by emphasizing that the Lord Jesus Christ embodies the greatest and most suitable good for our souls. He describes Christ as a universal, matchless, and eternal good, highlighting that in Him we find mercy for pardon, power for salvation, wisdom for guidance, grace for enrichment, and righteousness for our needs. Brooks encourages believers to recognize that everything they require for their spiritual state is found in Christ.

Charles Finney's sermon 'The Wants of Man and Their Supply' emphasizes the inherent needs of humanity—physical, intellectual, and spiritual. He illustrates how, like the prodigal son, individuals often find themselves in a state of want, leading to a deep yearning for God and righteousness. Finney argues that true fulfillment can only be found in God, as He is the ultimate source that satisfies our moral and spiritual cravings. The sermon calls for self-examination and recognition of these needs, urging listeners to seek God earnestly to find true contentment and purpose. Ultimately, Finney stresses that neglecting these spiritual needs leads to profound wretchedness.