Zac Poonen emphasizes that what the world values is detestable to God, particularly the love of money, which leads to numerous negative consequences for believers. He warns that worldly honor should be rejected, as it distracts from true riches found in faithfulness to God. Poonen also highlights that no one can truly harm us except ourselves, as God works all things for the good of those who love Him and are called according to His purpose. He encourages believers to be zealous for good, asserting that this zeal protects them from harm. Poonen shares his personal testimony of experiencing no harm throughout his life, attributing this to his faithfulness and trust in God's plan.