John Gill discusses the lineage and descent of the Messiah, emphasizing that He was prophesied to arise from the nation of Israel, specifically from the tribe of Judah and the house of David. He highlights that the Messiah's identity is rooted in Old Testament prophecies, which affirm that Jesus fulfills these requirements as a descendant of Abraham, Judah, and David. Gill argues against claims that the Messiah could come from other nations or tribes, asserting that Jesus' lineage is crucial to His role as the Savior. He also addresses misconceptions regarding the genealogy of Jesus, clarifying that both Mary and Joseph were of David's line, thus legitimizing Jesus' claim to the throne. Ultimately, Gill underscores the significance of Jesus' heritage in establishing His authority and identity as the Messiah.