Keith Parker discusses the significance of Israel in the context of God's plan for the shaking of the nations, emphasizing that this shaking is a divine process to remove what is not of God and establish His purposes. He highlights Israel's unique calling as a priestly nation, chosen to represent God to the world, and reassures that God's gifts and calling for Israel remain irrevocable despite their historical failures. Parker encourages believers to pray for Israel's restoration and the spread of the Gospel, asserting that the fulfillment of God's promises is imminent as we witness the signs of the times.