Thomas Brooks emphasizes the inherent vanity of man, stating that even at his best, he is in constant need of various essentials for survival. In contrast, God is portrayed as the embodiment of infinite perfection, self-sufficient and lacking nothing, possessing all excellencies within Himself. Brooks encourages Christians to recognize God as their all-sufficient portion, capable of providing protection, direction, mercy, and grace. He highlights that God encompasses all good and glory, fulfilling every need and desire of the soul. Ultimately, Brooks calls believers to find their complete satisfaction and security in God alone.

Thomas Brooks emphasizes the profound truth that every man, at his best state, is ultimately vanity, as stated in Psalms 39:5. He reflects on the fall of Adam, illustrating how humanity has devolved from its original glory to a state of emptiness and insignificance, likening man to dust, a shadow, and a comprehensive vanity. Brooks argues that despite any earthly honors or comforts, all are rendered meaningless in light of man's fallen nature. He poignantly describes the tragic transformation of man from the image of God to a burden to himself and heaven. The sermon serves as a sobering reminder of the need for redemption and the futility of relying on worldly achievements.