William MacDonald addresses the theme of human folly and its consequences, emphasizing how individuals often blame God for the ruin brought upon themselves by their own sinful choices. He illustrates this with examples of those who, after falling into immorality, turn against their faith and God instead of repenting. MacDonald highlights that apostasy frequently stems from moral failure, and that the hatred of God in the human heart is often a response to the light that exposes sin. He concludes that the reluctance to accept God's truth is deeply rooted in moral issues rather than intellectual doubts.