John Gill addresses the corruption of human nature, emphasizing that all individuals inherit a depraved nature from Adam's sin. He argues that this universal corruption is acknowledged by both heathens and scripture, asserting that no one is born pure and that all are under the dominion of sin. Gill explains that this inherent sinfulness manifests in every aspect of human life, from thoughts to actions, and highlights the necessity of redemption through Christ and regeneration by the Holy Spirit. He concludes that understanding this corruption is crucial for recognizing the need for salvation and the transformative power of God's grace.

Theodore Epp emphasizes the inseparable truths of recognizing God's holiness and our own depravity, as illustrated in Job 42:1-6. Job's profound encounter with God led him to a deep understanding of his own vileness, moving beyond mere acknowledgment to a personal confession of his unworthiness. This intimate revelation is a work of the Spirit, prompting a genuine self-abhorrence that manifests in humility and grace towards others. Epp highlights that true humility is not just a profession but is reflected in our attitudes and responses to others, especially when faced with insult or injury. Ultimately, a vision of God's righteousness compels us to confront our own shortcomings and fosters a contrite heart before Him.