A.W. Pink emphasizes the significance of Jude's prayer in the context of the somber warnings against apostasy within the Church. He highlights the dangers posed by false teachers who distort the grace of God, leading many astray, and contrasts this with the assurance of God's ability to keep believers from falling. Pink urges Christians to actively contend for their faith and maintain their love for God, while also addressing the need for vigilance against the creeping corruption in the Church. The sermon concludes with a powerful reminder of God's preserving grace amidst the challenges of faith.