T. Austin-Sparks emphasizes the spiritual pilgrimage of the Christian life, illustrating that the journey begins with a decisive separation from the world and progresses into a deeper conflict with the natural man within. He highlights Abraham's journey, where the initial call to leave his homeland leads to a new battle against the remnants of the old life, represented by Lot. The sermon stresses that true oneness with God requires not only leaving the world behind but also confronting and overcoming the natural self that clings to us. Sparks uses the story of Lot to illustrate the dangers of allowing the natural man to hinder spiritual progress, ultimately calling for a crisis of separation to fully embrace God's purpose. The message concludes with a call for self-examination and surrender to God’s will.