Zac Poonen emphasizes the importance of having a burden and concern for God's work, drawing parallels between the movements of Israel from Babylon to Jerusalem and the current state of the church. He highlights the examples of Daniel, Ezra, and Nehemiah, who fasted and prayed for the advancement of God's kingdom, showing that true leaders are those who selflessly intercede for others rather than criticize. Poonen urges believers to pray for those who preach God's Word, recognizing that they are often targets of spiritual attacks. He calls for a return to genuine shepherding, where leaders are committed to the well-being of their flock and are driven by a deep concern for their spiritual health. The sermon concludes with a plea for more shepherds who are aligned with God's heart to rise up in the church.