I think the problem stems from the preposition
Properly the same as H5920 used as a preposition (in the singular or plural, often with prefix, or as conjugation with a particle following); above, over, upon, or against (yet always in this last relation with a downward aspect) in a great variety of applications: - above, according to (-ly), after, (as) against, among, and, X as, at, because of, beside (the rest of), between, beyond the time, X both and, by (reason of), X had the charge of, concerning for, in (that), (forth, out) of, (from) (off), (up-) on, over, than, through (-out), to, touching, X with.
The interpretations are ringing the changes on whether the preposition means opposite/against in the sense of spacial location or fraternal conflict. You pays your money and takes your choice. ;-) The ASV which is very reliable in the OT has And they dwelt from Havilah unto Shur that is before Egypt, as thou goest toward Assyria. He abode over against all his brethren. (Gen 25:18 ASV) The ASV almost certainly has in mind the original prophecy relating to Ishmael;And he shall be as a wild ass among men; his hand shall be against every man, and every man's hand against him; and he shall dwell over against all his brethren. (Gen 16:12 ASV) and here again we have the ambiguity regarding location or conflict although from the earlier part of the verse conflict seems the more likely.